( PMCB ), a clinical stage biotechnology company focused on developing targeted treatments for cancer and diabetes using its signature live-cell encapsulation technology, Cell-in-a-Box, today announced that recent research performed at the Ann and Robert H. Lurie Children’s Hospital of Chicago and Northwestern Universitys Feinberg School of Medicine and published in the journal Childs Nervous System provides further Nice words support for PharmaCytes efforts to develop a targeted cannabinoid-based chemotherapy for brain cancer utilizing its technology. The article, titled Spontaneous involution of pediatric low-grade gliomas: high expression of cannabinoid receptor 1 (CNR1) at the time of diagnosis may indicate involvement of the endocannabinoid system, showed that activators of the endocannabinoid system offer potential therapeutic opportunities for children with pediatric low-grade gliomas (P-LGG). http://tweethudsonsanders.rachelstevens.us/2016/08/08/without-proper-hydration-the-healing-mechanisms-of-the-skin-cease-to-function-adversely-affecting-the-skins-ability-to-receive-nutrients-and-repair-itselfP-LGGs consist of a mixed group of brain tumors that represent the majority of central nervous system tumors in children. Some P-LGGs exhibit spontaneous shrinking after less than total surgical removal. For the first time, spontaneous shrinking of P-LGG has been suggested to be induced by endocannabinoids. PharmaCytes Chief Executive Officer, Kenneth L. Waggoner, commented, It is clear that PharmaCyte is on the right track to developing targeted therapies for deadly cancers. The research reported in the journal Childs Nervous System, as well as other research, continues to demonstrate the anti-cancer properties of cannabinoids. We remain confident that Cell-in-a-Box offers a safe and versatile platform for targeted chemotherapy delivery to cancerous tumors in the brain. The researchers investigated molecular indicators of spontaneous shrinking in P-LGGs and found that tumors that remained stable or had spontaneous shrinking after surgery had significantly higher levels of expression of the CNR1 gene at the time of diagnosis.
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